Benefits and Applications of ENDORET® in Implantology
INCREASED PREDICTABILITY
- BTI® implants wetted with ENDORET® have a high survival rate. (19) (20) (21) (22)
- When the surface of the implants is wetted with ENDORET® liquid, a fibrin membrane is formed and adheres to the surface of the implant, releasing growth factors and improving the osseointegration.
- The nano-rough surface of BTI® implants is specially designed to boost the biological effects of ENDORET®.
- Wetting with ENDORET® increased the trabecular thickness and maturity of the bone.
Survival rates reported in clinical studies:
- Up to 5 years follow-up study 5787 implants. 99.2% (19)
- Up to 5 years follow-up study 1139 immediate load implants. 99.3% (17)
- Up to 8 years follow-up study 1287 short implants. 99.3% ((18)
- 10-12 years follow-up study 111 short implants. 98.9% (22)
Histomorphometric evaluation of the bone-implant contact surface (bic) after two months in goats (23)
TREATMENT OF POST-EXTRACTION SOCKET
The application of ENDORET® in the treatment of post-extraction socket reduces inflammation and pain, accelerates soft tissues healing and promotes bone regeneration as it has been demostrated in several clinical trials. (11) (14) (24)
The survival rate of inmediately placed dental implant, after tooth extraction, has been 98% in a clinical study. It is a safe, effective and predictable treatment. (25)
CONTROL
DAY 1
Defect after the dental extraction.
DAY 15
Epithelialisation after 15 days. Incomplete closure of the gingival tissue is observed.
ENDORET® (PRGF®)
DAY 1
Extraction and placement of ENDORET®.
DAY 15
Complete closure of the gingiva after 15 days.
REDUCED RISK OF OSTEONECROSIS
ENDORET® in the treatment of BRONJ
Treatment with ENDORET®, after resecting the necrotic bone of BRONJ, may enhance vascularization and regeneration of bone and epithelial tissue as shown in a clinical trial.
(26)
ENDORET® was effective in the surgical treatment of bisphosphonate-associated osteonecrosis of the jaw, achieving closure of the defect in 32 patients in a clinical prospective study.
(26)
The results of various clinical studies suggest that treatment with ENDORET® can reduce the risk of BRONJ after a dental extraction in high-risk patients under treatment with bisphosphonates.
(27) (28)
| Treatment |
Number of extractions |
Osteonecrosis of the maxilla |
| Control |
267 |
5 |
| ENDORET® (PRGF®) |
542 |
0 |
Clinical trial of the prevention of bisphosphonate-associated osteonecrosis of the jaw (BRONJ) (27)
1. ENDORET® (PRGF®)
2. ENDORET® (PRGF®)
3. ENDORET® (PRGF®)
CONTROL
PREPARATION OF GRAFTS
ENDORET® can be used to agglutinate a biomaterial, making it easier to handle and improving its osteoconductive and biological properties. (10) (29) (30) (31) (32)
TREATMENT OF ATROPHIC MAXILLAE
ENDORET® improves the tissue regeneration and due to its versatility can be used in various surgical techniques.
A. LATERAL BONE AUGMENTATION
The alveolar ridge expansion and the alveolar ridge split techniques in combination with ENDORET® can achieve an average bone expansion of 3.35 mm.
(33) (34)
Distribution of width values (mm) of the initial and final crests.
The use of ENDORET® in combination with the block graft improves the tissue healing, avoiding the exposure of the graft and improves the post-operative recovery of the patient.
(35)
Two-stage crestal split treatment
Longitudinal corticotomy with ultrasound tip
Use of bone grafts and fibrin membranes
After 3 months
After 6 months
B. SINUS ELEVATION
ENDORET® reduces inflammation and pain. It increases the new bone formation.
(10) (31) (36)
ENDORET® is effective in the treatment of performations in the Schneider membrane.
(30)
Split-mouth study of ENDORET® vs. Control in a sinus elevation procedure with a lateral approach. (32)
Control treatment
Treatment with ENDORET®
C. VERTICAL BONE REGENERATION
The combination of ENDORET® graft with short and extra-short implants makes possible the rehabilitation of atrophic mandible without the need of more aggressive techniques.
(37) (38)
PERIODONTAL REGENERATION
ENDORET® may be beneficial in the field of the mucogingival surgery.
(39)
Treatment of gingival defects
